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00:00:00 Hello everyone, thank you so much for joining me today to watch this video presentation on polycystic ovary syndrome and how it affects fertility. So in this video I'll be giving you a little bit of background about PCOS, the symptoms it causes and what you have to consider if you are starting your fertility journey or trying to conceive a child and
00:00:22 you have PCOS. So a little introduction to polycystic ovary syndrome, it is a hormonal So a little introduction to polycystic ovary syndrome, it is a hormonal disorder, it affects one in ten women worldwide, those who are of a reproductive age. I know from working in clinic and from meeting so many women and treating them who have PCOS, their main concern is
00:00:47 am I going to be able to have a family of my own easily, will I be able to carry a child, will I find it a huge struggle to get pregnant. And this is why I wanted to make this video to let people know that there are many areas of support for women with PCOS to let people know that there are many areas of support for women with PCOS when it comes to fertility issues and conceiving a child and making sure that your pregnancy
00:01:11 is healthy and as pleasurable as possible. Now I would only use a holistic approach when dealing with the women I see when it comes to PCOS, there are pharmaceutical measures you can take to manage symptoms of PCOS. And the reason I have put in but prevent conception is because although later And the reason I have put in but prevent conception is because although later
00:01:33 there are medications to help with ovulation which I will talk about in later slides, often when women are initially diagnosed with PCOS during their teen years, doctors will prescribe the contraceptive pill and as we all know that if you are on the contraceptive pill you cannot get pregnant. So although the contraceptive pill we usually help to balance hormones, there
00:01:58 might be a trial and error period during the initial stages of starting the medication but trial and error period during the initial stages of starting the medication but they will usually lower and androgens or increase estrogen and progesterone to match them. So your symptoms of PCOS will be managed and you will be leading a very happy life . However
00:02:15 when it comes to the time when you want to start a family you have to go off the pill, symptoms come back and you are then met with the challenges of managing PCOS without the contraceptive pill. contraceptive pill. So a little bit more about what PCOS is exactly. So although I said in the last slide it is
00:02:37 a hormonal disorder which it is. It is also seen as an inflammatory condition and this is because with lots of women who I see in clinic when I look at their blood reports their inflammatory markers are usually extremely high. This is due sometimes to insulin resistant and a lot of inflammation in the body caused by high androgens. So the and a lot of inflammation in the body caused by high androgens. So the
00:03:01 imbalance reproductive hormones that is related to when it comes to PCOS, high androgen hormones. And rogens are usually seen as the male hormones although both sexes do have them. And in PCOS the testosterone course will tend to go higher than other hormones such as estrogen, progester one, follicle stimulating hormone. The more female hormones that help with ovulation and egg health. So
00:03:23 hormone. The more female hormones that help with ovulation and egg health. So that is what happens when you have PCOS. And just to describe exactly what happens, so if you look in the diagram here, enlarged ovaries containing multiple cysts is what polycystic ovary syndrome actually is. And what the cysts are are follicles that are under developed.
00:03:54 So in women's ovaries we have follicles and they basically sacs that help to So in women's ovaries we have follicles and they basically sacs that help to develop and mature the eggs and then the egg is released during ovulation and then all going well if you are trying for a baby, that egg and sperm will come together and you will become pregnant. However with polycystic ovary syndrome for some reason we don't know what
00:04:20 causes it but these follicles are underdeveloped and therefore the egg is underdeveloped and doesn't mature and doesn't release. So there is no ovulation and therefore women can go for and doesn't release. So there is no ovulation and therefore women can go for very long periods of time without having any menstrual bleeding so they won't have a period. Sometimes it
00:04:37 can be a few months. I've seen cases where I can be years where a woman will not have a period. So that is essentially what PCOS is and what's going on in the body when you've been diagnosed with it. So how does PCOS affect fertility? Well number one as I 've already discussed irregular ovulation because you are often not ovulating, no egg is discussed irregular ovulation because you are often not ovulating, no egg is
00:05:00 released and you don't have a period, you cannot conceive. If there's no egg to fertil ize then a pregnancy is not going to happen and that is due to the actual condition itself with the follicles, not releasing the eggs because they're underdeveloped but also due to hormonal imbalances as I mentioned earlier, the androgen dominance, the male hormones surging in the body will
00:05:22 prevent ovulation also. Another way that it affects your fertility is insulin resistance. Again the insulin resistance, many many women who have PCOS are diagnosed with the insulin resistance, many many women who have PCOS are diagnosed with insulin resistance. So insulin levels are high, so fasting insulin is high in the blood and then we notice there's
00:05:39 a negative correlation between high fasting insulin and low sex hormone binding globulin. So that again is low and that interrupts fertility and hormones working properly in the body. And with insulin resistance, all fin comes at weight gain. So then you have to And with insulin resistance, all fin comes at weight gain. So then you have to consider BMI, if you have a high BMI over 25 that is also not good for your fertility
00:06:15 and ability to conceive. So I have a lot of women with PCOS who will say, you know, I feel like I'm eating all the right things, I'm exercising, I'm quite healthy in comparison to many people yet, I'm consistently gaining weight or I'm not able to lose weight. These are yet, I'm consistently gaining weight or I'm not able to lose weight. These are one of
00:06:31 the symptoms that come with PCOS but it is about getting the right type of nutrition and right type of exercise in order to manage your BMI so that you get within a nice healthy normal range and feel healthy when you do come to getting pregnant. So when it comes to fertility issues because you have PCOS, what are the treatments you can seek? Well, firstly, I will have to talk about lifestyle changes, mainly
00:06:55 can seek? Well, firstly, I will have to talk about lifestyle changes, mainly nutrition and exercise because that's the area I work in. It's amazing, the amount of nutritional interventions, different strategies, what to leave out, what to have more of, what to limit in certain circumstances and also how you eat, what type of exercise you 're doing,
00:07:22 what is some that work better than others when it comes to PCOS in terms of helping insulin resistance in the body and other lifestyle factors, what's work, life, sleep, resistance in the body and other lifestyle factors, what's work, life, sleep, how could that be improved, what are the main stresses going on, are there any other medications that could be interrupting and also supplements, so what supplements are you
00:07:42 taking, what are the dosage, are they correct for PCOS, are there some that you shouldn't bother taking at all? And many people see so much change and such improvements in symptoms of PCOS and can happily and quite easily conceive a child once they adjust these and can happily and quite easily conceive a child once they adjust these factors in
00:08:02 their life. Number two on the list is medications to induce ovulation. So you have the first two medications on their oral medications that help to increase follicle stimulating hormone and therefore an egg is released and ovulation occurs and then once an egg is there the chances of conception of course are higher. If the first two medications or any sort of
00:08:28 oral medication for induced ovulation don't work, there are injectable hormones oral medication for induced ovulation don't work, there are injectable hormones that you can take but they're a little bit more severe and sometimes produce more than one egg leading to multiple pregnancies which can be a good thing but there's risks involved in that also. Number three is metformin, so metformin is used a lot with type 2 diabetes but
00:08:56 it's also used for people with women with PCOS and it does help improve insulin used for people with women with PCOS and it does help improve insulin sensitivity, helps to regulate periods and can improve ovulation. One thing I would just like to state and there are other videos that you can watch where I talk about supplements that work almost
00:09:16 or just as well as metformin which you would not need a prescription for however I would always advise talking to someone who knows what they're talking about a health care practitioner about these supplements first before you go buying them and taking them because about these supplements first before you go buying them and taking them because dosage is key. And then number four on the list, so assisted reproductive technology
00:09:42 so in vitro fertilization or IVF. Now I've put it number four on the list because it really is the last resort you should go for. I work for an IVF clinic and they can't, you know the treatment can be very successful and successful for a lot of people however this, there is this thought process that if I've been trying for two years I think it's
00:09:59 this thought process that if I've been trying for two years I think it's normally the length of time they give and I haven't conceived now it's time for IVF. I would insist or not insist but I would really recommend that you have tried all of the above factors for consideration first before you go to IVF mainly because well one it's very expensive. Two it can be
00:10:28 quite traumatic and invasive and can really take its toll on your physical well quite traumatic and invasive and can really take its toll on your physical well -being and how you feel emotionally and physically. And three the most important one there's not a 100% guaranteed success rate okay. A lot of people will go through IVF for multiple rounds because it doesn't happen first or second time and again the cost goes
00:10:54 up and the toll on your body goes up as well. So please try number one, two or three the toll on your body goes up as well. So please try number one, two or three they can go either way possibly three before two but certainly nutrition and lifestyle factors are your first important call when you're trying to conceive and you don't feel like
00:11:14 you're getting anywhere that's the area you look at first. So just to conclude number one PCOS impacts fertility and brings challenges for those trying to conceive. This is very true most people will find it a little bit trying to conceive. This is very true most people will find it a little bit more difficult to get pregnant when they have PCOS. However moving on to number two many women do conceive
00:11:42 sometimes naturally or with minor adjustments even if they do have PCOS. So please try and look at what you can first consider in order to manage your symptoms of PCOS well and hopefully not have any major problems when it comes to conceiving. And of course number not have any major problems when it comes to conceiving. And of course number three this is the most important point I want to mention right at the end of this
00:12:09 presentation. Understanding how PCOS affects the body is key and that is your final thought for the day. Once you understand the condition once you talk with someone and get the right support that you need and have them help you on your fertility journey or on your PCOS journey need and have them help you on your fertility journey or on your PCOS journey if you're
00:12:33 not ready and for to get pregnant now. Knowing that someone is there to talk you through what you need to consider what changes need to happen and how you can easily move that into your life well is the best way forward because once you know what's going on internally and how to treat it it's a game changer and you really can make huge improvements not
00:12:58 only to your chances of conception but also to your health in general. So thank only to your chances of conception but also to your health in general. So thank you so much for listening and I look forward to making some more videos about PCOS and helping you through your fertility journey. Thanks.